INDICATIONS
For the symptomatic treatment of mild to moderate pain and / or fever.
DOSAGE & ADMINISTRATIONS
Paracetamol (Pyritas) is given by intravenous infusion over 15 minutes; dosage may be calculated by weight as follows:
-Patients weighing over 50kg, single doses of 1g every 4 or more hours, to a maximum of 4g daily
-From 33 to 50kg, single doses of 15mg/kg every 4 or more hours, to a maximum of 60mg/kg or 3g daily (whichever is less).
DRUG INTERACTIONS
The risk of Paracetamol toxicity may be increased in patients receiving other potentially hepatotoxic drugs or drugs that induce liver microsomal enzymes. The absorption of Paracetamol may be accelerated by drugs such as metoclopramide. Excretion may be affected and plasma concentrations altered when given with probenecid.